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 Publikationen

Oral Presentations

Mahler M, Koenig M, Senécal JL, Csernok E, Arnett FC, Riemekasten G, Fritzler MJ: Sero-Clinical aspects of autoantibodies to a PM/Scl peptide with special emphasis on a cohort of 495 systemic sclerosis patients . 5th Congress on autoimmunity held in Sorrento, Italy 2006.
Abstract   PDF

Mahler M, Greidinger EL, Fritzler MJ: Serological and clinical characterization of anti-DNA and anti-PM/Scl double positive samples. 5th Congress on autoimmunity held in Sorrento, Italy 2006.
Abstract   PDF

Mahler M. and Fritzler MJ: Novel aspects of autoantibodies to the human exosome (PM/Scl complex). 8th Dresden Symposium on Autoantibodies, Germany 2007. 

Mahler M, Lorenz C, Fooke M and Kleine-Tebbe J: Comparison between skin prick test and a reversed enzyme allergo-sorbent test. 20th World allergy congress held in Bangkok, Thailand 2007. 
Abstract    PDF

Mahler M: Autoantibodies to the ribosomal P antigens in autoimmunity, allergy and infectious diseases.   10th International Workshop on Autoantibodies & Autoimmunity held in Guadalajara, Mexico 2008. 

Mahler M. and Fritzler MJ: Novel diagnostic aspects of anti-PM/Scl  autoantibodies. 6th Congress on autoimmunity held in Porto, Portugal 2008.
Abstract    PDF

Schulte-Pelkum J, Simon T, Szmyrka-Kaczmarek M, Fritzler MJ, Mahler M: Latest update on the Ro/SS-A autoantibody system. 6th Congress on autoimmunity held in Porto, Portugal 2008.  
Abstract    PDF  

Mahler M, Lucassen R, Fooke M: Reliable rapid detection of allergen-specific and total IgE in the diagnosis of type I hypersensitivity using a novel allergy lateral flow assay (ALFA). The European Histamine Research Society 38th Annual Meeting held in Fulda, Germany 2009.

Lucassen R, Mahler M, van Helden J, Fooke M: Evaluation of an allergy lateral flow assay for the detection of specific IgE to food allergens. 28th Congress of the European Academy of Allergology and Clinical Immunology held in Warsaw, Poland 2009.
Abstract    PDF 

Mahler M, Fritzler MJ: Peptide resolved diagnostics in systemic autoimmune diseases: Potentials and Pitfalls. 9th Dresden Symposium on Autoantibodies, Germany 2009. 


Poster Presentations

Kleine-Tebbe J, Breuer K, Lepp U, Vieths S, Worm M, Kunkel G, Wahn U, Lau S: Allergen-sepcific IgE-values to inhalant and food allergens – Comparison between two commercial immunoassays: Dr. Fooke ALLERG-O-LIQ versus Pharmacia CAP-System. 23rd EAACI congress held in Paris, France, 2004. 
Poster PDF

Duyan I, Mahler M, Hoff M, Fooke M: Technical and clinical evaluation of a fully automated Reversed Enzyme Allergo Sorbent Test (REAST) using liquid biotinylated allergens. 13th National Allergy and Clinical Immunology Congress held in Izmir, Turkey 2005.
Poster PDF

Fritzler MJ, Mahler M,  Fritzler ML: Autoantibodies in a cohort of sera that contain anti-Jo-1 (histidyl-tRNA synthetase) antibodies. 9th International Workshop on Autoantibodies & Autoimmunity held in Gainesville, Florida, USA 2005. 
Abstract  PDF   Poster  PDF

Mahler M, Raijmakers R, Fritzler ML, Fritzler MJ: Anti-PM1-Alpha antibodies are frequently accompanied by antibodies to GW bodies in patients with PM/Scl overlap syndrome. 9th International Workshop on Autoantibodies & Autoimmunity held in Gainesville, Florida, USA 2005. 
Abstract  PDF   Poster  PDF

Kessenbrock K, Fritzler MJ, Mahler M: Structural analysis of the major ribosomal P epitope C22. 9th International Workshop on Autoantibodies & Autoimmunity held in Gainesville, Florida, USA 2005. 
Abstract  PDF  Poster  PDF

Lucassen R, Mahler M, Fooke M: Development and evaluation of a rapid assay for the diagnosis of type I allergies. 26th EAACI congress held in Gothenburg, Sweden, 2007. Abstract published in Allergy 2007, 62 (Suppl. 83, poster 1242): 167-551.
Abstract   PDF  Poster  PDF

Mahler M, Lorenz C, Lucassen L, Fooke M, Kleine-Tebbe K: Clinical evaluation of a new allergy lateral flow assay for professional and home use. 20th World allergy congress held in Bangkok, Thailand 2007.   
Abstract    PDF

Sun B, Mei J, Jing L, Zhong N: Allergen-specific IgE to inhalant and food allergens and total IgE values in China – Comparison between two commercial immunoassays: Dr. Fooke ALLERG-O-LIQ versus Phadia ImmunoCAP®System. 20th World allergy congress held in Bangkok, Thailand 2007. 
Abstract  PDF  Poster  PDF

Sager A, Lauter H: Sensitization and clinical relevance of ragweed pollen in patients with intermittent rhinoconjunctivitis. 20th World allergy congress held in Bangkok, Thailand 2007. Abstract published in World Allergy Organization Journal & November 2007.
Abstract  PDF

Lauter H, Sager A: Sensibilisierung und klinische Relevanz von Beifuß-Ambrosie im Hochsauerland bei Patienten mit Heuschnupfen. Allergo J 2007, 16: (Poster 34) S64.

Fritzler MJ, Ngo J, Hou H, Mahler M: Limited reliability of the indirect immunofluorescence technique for the detection of anti-Rib-P antibodies. 10th International Workshop on Autoantibodies & Autoimmunity held in Guadalajara, Mexico 2008.
Poster PDF

Mahler M, Eissfeller P, Silverman ED, Fritzler MJ: Diagnostic value of a novel ANA Screen ELISA. 10th International Workshop on Autoantibodies & Autoimmunity held in Guadalajara, Mexico 2008.
Poster PDF

Lucassen R, Mahler M, Fooke M: Development and evaluation of a new rapid assay for semi-quantitative detection of total IgE in human serum and cappilary blood.  27th Congress of the European Academy of Allergology and Clinical Immunology held in Barcelona, Spain 2008.
Poster PDF

Lucassen R, Fooke M, Lorenz C, Kleine-Tebbe J, Mahler M: Evaluation of a rapid assay for the diagnosis of type I allergy.  27th Congress of the European Academy of Allergology and Clinical Immunology held in Barcelona, Spain 2008.
Poster PDF

Mahler M, Eissfeller P, Fritzler ML and Fritzler MJ: Anti-PCNA antibodies in samples with cell cycle dependent, PCNA-like indirect immunofluorescence staining pattern. 6th Congress on autoimmunity held in Porto, Portugal 2008.
Poster PDF

Mahler M, Mierau R, Humbel R and Fritzler MJ: Anti-PM1-Alpha antibodies: Analytical evaluation in two centers. 6th Congress on autoimmunity held in Porto, Portugal 2008.
Poster PDF

Schulte-Pelkum J, Mahler M, Szmyrka-Kaczmarek M, Petschinka M, Simon M and Fritzler MJ: Evaluation of recombinant Ro60 for diagnostic use in AI-Line ELISA. 6th Congress on autoimmunity held in Porto, Portugal 2008.
Poster PDF

Mahler M, Petschinka M, Lüttich T, Hiepe F, Szmyrka-Kaczmarek M and Fritzler MJ: Anti-topo-I/Scl-70 autoantibodies in systemic lupus erythematosus: Myth or reality? 6th Congress on autoimmunity held in Porto, Portugal 2008.
Poster  PDF

Mahler M, Fooke M: Detection of allergen-specific IgE using the ALLERG-O-LIQ System based on the Reversed-enzyme-allergo-sorbent-test. The European Histamine Research Society 28th Annual Meeting held in Fulda, Germany 2009.
Poster  PDF

Ngo J, Mahler M, Fritzler MJ: A Comparison between old and newer methods for the detection of Anti-Ribosomal P Autoantibodies. 2009 Canadian Rheumatology Association Conference and annual meeting held in Delta Kananaskis, Kananaskis, Alberta, Canada 2009.
Poster PDF

Lucassen R, Schulte-Pelkum J, Mahler M, Kleine-Tebbe J, Csuvarszki C, Fooke M: Development and evaluation of a scanner based allergy lateral flow assay for the determination of specific IgE. 28th Congress of the European Academy of Allergology and Clinical Immunology held in Warsaw, Poland 2009.
Poster  PDF

Mahler M, Agmon-Levin N, van Liempt M, Shoenfeldt Y, Waka A, Hiepe F, Swart A, et al.: Multi-center evaluation of autoantibodies to the major ribosomal P epitope C22. Ann Rheum Dis 2009, 28: Suppl 3, 514.
Poster  PDF

Mahler M, van Liempt M, Schulte-Pelkum J, Schneider S, Alexander T, Kromminga A, Fooke M, Hiepe F: Evaluation of a novel dsDNA ELISA for SLE disease activity measurement. 9th Dresden Symposium on Autoantibodies, Germany 2009.
Poster  PDF

Mahler M, Siegmund M, Meyer W, Petschinka M, Fritzler MJ: Anti-PM/Scl-antibodies in systemic sclerosis: Comparison between PM1-Alpha ELISA and a line assay with recombinant PM/Scl-75c and PM/Scl-100. 9th Dresden Symposium on Autoantibodies, Germany 2009.
Poster  PDF

Swart A, Mahler M, Fritzler MJ: The cell cycle protein Nop52 is a candidate target autoantigen. 9th Dresden Symposium on Autoantibodies, Germany 2009.
Poster   PDF

Mahler M, Schulte-Pelkum J, van Liempt M, Wither JE, Fooke M, Fritzler MJ: Anti-CENP-A and CENP-B antibodies in SLE. 7th International Congress on Autoimmunity, Slowenia 2010.
Poster   PDF

Pfender N, Mahler M, Offermann N, Lucassen R, Fooke M, Jakob T: Comparison between two systems for the detection of specific IgE to bee and wasp venom. 29th Congress of the European Academy of Allergology and Clinical Immunology, England 2010.
Poster     PDF

Pfender N, Mahler M, Offermann N, Lucassen R, Fooke M, Jakob T: Evaluation of a novel rapid test system for the detection of specific IgE to be and wasp venom. 29th Congress of the European Academy of Allergology and Clinical Immunology, England 2010. 
Poster     PDF     

Lucassen R, Pfender N, Mahler M, Offermann N, Fooke M, Jacob T: Evaluation of a rapid test sysem for the detection of specific IgE to cross-reactive carbohydrates. 29th Congress of the European Academy of Allergology and Clinical Immunology, England 2010.
Poster     PDF    


Manuscripts

Kleine-Tebbe J, Breuer K, Lepp U, Vieths S, Worm M, Kunkel G, Wahn U und Lau S: Spezifische IgE-Werte gegen Aero- und Nahrungsmittelallergene im Vergleich: Dr. Fooke ALLERG-O-LIQ und Pharmacia CAP-System.  Allergologie 2004,4.

Mahler M, Raijmakers R, Dähnrich C, Blüthner M and Fritzler MJ: Clinical evaluation of autoantibodies to a novel PM/Scl peptide antigen. Arthritis Research & Therapy 2005, 7:R704-R713.
Manuscript  PDF

Mahler M, Fritzler MJ: Anti-dsDNA antibody testing in the clinic: Farr or ELISA? Nat Clin Pract Rheumatol 2007, 3:72-3.

Mahler M, Raijmakers R: Novel aspects of autoantibodies to the PM/Scl complex: Clinical, genetic and diagnostic insights. Autoimmun Rev 2007, 6:432-7. 

Mahler M, Waka A, Hiepe F, Fritzler MJ: Effect of dsDNA binding to SmD-derived peptides on clinical accuracy in the diagnosis of systemic lupus erythematosus. Arthritis Res Ther 2007, 9:R68.
Manuscript  PDF

Mahler M, Greidinger EL, Szmyrka M, Kromminga A, Fritzler MJ: Serological and Clinical Characterization of Anti-dsDNA and Anti-PM/Scl Double-Positive Patients. Ann N Y Acad Sci 2007, 1109:311-21. 

Kessenbrock K, Raijmakers R, Fritzler MJ, Mahler M: Synthetic Peptides: The Future of Patient Management in Systemic Rheumatic Diseases? Curr Med Chem 2007, 14:2831-8. 

Lucassen R, Fooke M, Kleine-Tebbe J, Mahler M: Development and Evaluation of a Rapid Assay for the Diagnosis of IgE-mediated Type I Allergies. J Investig Allergol Clin Immunol 2008, 18:223-4.
Manuscript  PDF

Sun B, Mahler M, Mei J, Jing L, Zhong N: Allergen-specific IgE to inhalant and food allergens and total IgE values in China – Comparison between two commercial immunoassays: Dr. Fooke ALLERG-O-LIQ versus Phadia ImmunoCAP® System. J Invest All Clin Immunol 2008, 18:319-321.
Manuscript PDF  

Mahler M, Ngo J, Schulte-Pelkum J, Luettich T, Fritzler MJ: Limited reliability of the indirect immunofluorescence technique for the detection of anti-Rib-P antibodies. Arthritis Res Ther 2008, 10:R131.           

Mahler M, Fritzler MJ: PM1-Alpha ELISA: The assay of choice for the detection of anti-PM/Scl autoantibodies? Autoimmun Rev 2009, 8:373-8.

Schulte-Pelkum J, Fritzler MJ, Mahler M: Latest update on the RO/SS-A autoantibody system. Autoimmunity Rev 2009, 8:632-637.

Mahler M, Fritzler MJ: The changing landscape of the clinical value of the PM7Scl autoantibody system. Arthritis Res Ther 2009, 11:106.
Manuscript  PDF

Mahler M, Fritzler MJ: AIT test has no problem in the detection of anti-ribosomal P - authors response.  Arthritis Res Ther 2009, 11:411.
Manuscript  PDF

Mahler M, Fritzler MJ: Epitope specificity and significance in systemic autoimmune diseases. Ann N Y Acad Sci 2010, 1183: 267-287.

Lucassen R, Schulte-Pelkum J, Csuvarszki C, Kleine-Tebbe J, Fooke M, Mahler M: Evaluation of a Novel Rapid Test System for the Detection of Allergic Sensitization to Timothy Grass Pollen against Estabilished Laboratory Methods and Skin Prick Test. Journal of Allergy 2010, Volume 2010: 1-4.

Mahler M, Silverman ED, Schulte-Pelkum J, Fritzler MJ: Anti-Scl-70 (topo-I) antibodies in SLE: Myth or reality? Autoimmun Rev 2010.

Maes L, Bockmans D, Verschueren P, Westhovens R, De Beeck KO, Vermeersch P et al.: Anti-PM/Scl-100 and anti-RNA-polymerase III antibodies in scleroderma. Clin Chim Acta 2010, 411: 965-971.

Mahler M, Maes L, Blockmans D, Westhovens R, Bossuyt X, Riemekasten G et al.: Clinical and serological evaluation of a novel CENP-A peptide based ELISA. Arthritis Res Ther 2010, 12: R99.


Book chapters

Eisfeller P, Pepperkok B, Luettich T, Mahler M, Jauris C, Fritzler MJ: The association of anti –SS-A/ Ro52 and anti-SS-A/Ro60 antibodies in different connective tissue diseases. In Prediction and Early Diagnosis of Disease by Autoantibodies: Reports on the 8th Dresden Symposium on Autoantibodies. Edited by Conrad K, et al., Lengerich: Pabst Science Publishers; 2007.   

Mahler M, Fritzler MJ: Novel aspects of autoantibodies to the human exosome (PM/Scl complex): Reports on the 8th Dresden Symposium on Autoantibodies. Edited by Conrad K, et al., Lengerich: Pabst Science Publishers; 2007.

Mahler M, Fritzler MJ: Peptide resolved diagnostics in systemic autoimmune diseases: Potentials and Pitfalls. Reports on the 9th Dresden Symposium on Autoantibodies. Edited by Conrad K, et al., Lengerich: Pabst Science Publishers; 2009.

 
 
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