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ARTHUS

ARTHUS

Artificial Human Sera (ARTHUS) for the Standardization of in-vitro Allergy Diagnostics

The availability of well-defined quality control sera (positive human sera) is essential for the development, production, evaluation, standardization and quality control for Allergy in-vitro Test Systems. However, human control sera are not existent for all allergens. In addition, serum samples from commercial serum banks (often serum pools) show often variable quality and are normally very expensive. Another reason for variable or different results between the test systems may be that the allergens are coming from different sources, raw materials and different manufacture processes, release procedures and storage conditions. Standardized reference material is not available for the determination of allergen-specific Immunoglobulin E. The use of artificial human sera could be a step for the standardization of Allergy in-vitro Test Systems.  

WHAT IS ARTHUS (Artificial Human sera)?

ARTHUS-sIgE controls are produced by fusion of the human IgE-Fc-region and allergen-specific antibodies from rabbits. The allergen-specific rabbit antibodies are generated by immunization with recombinant or highly purified allergens as well as allergen extracts. The fusion of the allergen-specific antibodies with the human IgE-Fc-region results in ARTHUS which can be used for the determination of human specific IgE antibodies.

ARTHUS-sIgE controls have to be handled as normal serum samples according to the instructions for use supplied with the kit.

WHY ARTHUS?

  • Solves the limited availability of human control sera, also for rare allergens
  • Bigger volumes in constant quality
  • Pure sera, no serum pools
  • High stability
  • Long shelf life at 2-8°C
  • Controls available for recombinant, highly purified native allergens and allergen extracts
  • Controls available for nearly all proteins
  • Functionality already confirmed in several studies

ARTHUS Autoimmune- and sIgG4 Diagnostics

ARTHUS-sIgG-Controls are available for the most important Autoimmune antigens. They can add to the standardization of Autoimmune diagnostics.

ARTHUS-sIgG4 Controls can add to the standardized diagnosis of follow-up of Immunotherapies. The functionality of ARTHUS-sIgG4 controls in different systems is already confirmed.

AVAILABLE ARTHUS CONTROLLS FOR sIgE

ARTHUS spec. for Allergen-Code REF
Penicilloyl G c1 07Ac0001 -01 / -10
Dermatophagoides pteronyssinus d1 07Ad0001 -01 / -10
Peanut f13 07Af0013 -01 / -10
Hazelnut f17 07Af0017 -01 / -10
Alpha – Lactalbumin f76 07Af0076 -01 / -10
Beta – Lactoglobulin f77 07Af0077 -01 / -10
Phospholipase A i11 07Ai0011 -01 / -10
Hevea brasiliensis k82 07Ak0082 -01 / -10
Aspergillus fumigatus m3 07Am0003 -01 / -10
Ves v 5 Wasp Venom ri305 07ARI305 -01 / -10
Bet v 1 Birch rt301 07ART301 -01 / -10

Here you will find our current ARTHUS – Flyer:

  • Allergy Diagnostic
    • ARTHUS
    • ALFA
    • EAST
    • REAST
    • Molecular Allergy Diagnostics
    • IgG / IgG4
  • Autoimmune Diagnostic
    • ELISA
    • Autoimmune Lateral Flow Assay
  • Microbiology
  • About Us
    • Events
    • Publications
    • Contact
    • Impressum
  • de
  • en
Copyright 2016 Dr. Fooke Laboratorien GmbH | All Rights Reserved
  • Allergy Diagnostic
    • ARTHUS
    • ALFA
    • EAST
    • REAST
    • Molecular Allergy Diagnostics
    • IgG / IgG4
  • Autoimmune Diagnostic
    • ELISA
    • Autoimmune Lateral Flow Assay
  • Microbiology
  • About Us
    • Events
    • Publications
    • Contact
    • Impressum
  • de
  • en
Dr. Fooke Laboratorien