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AUTOIMMUNE DIAGNOSTICS

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More confidence in autoimmune diagnostics

Autoimmune diseases are usually chronic inflammatory reactions in which the immune system makes antibodies against the body's own substances. These inflammatory reactions can lead to damage to the affected organs. The erroneous attack by the immune system usually continues for life without treatment or until the target structure is completely destroyed.

Despite intensive research, it is still not known why autoimmune diseases develop. Recognized hypotheses assume that autoimmune diseases are acquired through genetic predisposition in combination with external influences. If a person has a genetic predisposition and if there are also unfavorable environmental factors such as severe stress, infections or pregnancy, this can lead to an outbreak of autoimmune diseases.

AUTOIMMUNE DIAGNOSTICS

BAD LUCK AND BAD GENES

Symptoms and their consequences

The target structure of the autoimmune reaction can be a specific organ or the whole body (several organs and vascular system). Mixed forms with several autoimmune diseases are not uncommon.

The symptoms and their course depend primarily on which body structure, which organ or organ system is affected. Some autoimmune diseases affect a single organ (e.g. the thyroid gland in Hashimoto's thyroiditis), while others can affect structures throughout the body, e.g. the inner skin of the joints  rheumatoid arthritis .

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AUTOIMMUNE DISEASE

Frauenarzt

Organ-specific and systemic autoimmune diseases

The immune system is either directed selectively against a certain organ (e.g. thyroid, pancreas, intestine, skin, nerves) and then counts as one of the so-called organ-specific autoimmune diseases, or it acts against the entire system and thus causes a non-organ-specific, systemic autoimmune disease. In this case, the immune system attacks various body organs.

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GROUP 1:

Organ-specific  

Diseases.

Organ-specific autoimmune diseases:

  • multiple sclerosis 

  • Type 1 diabetes mellitus

  • Ulcerative colitis 

  • Pemphigus vulgaris 

  • Myasthenia gravis 

  • Graves disease 

ELISA

PM1 - Alpha ELISA

  • ELISA for the semi-quantitative determination of anti-PM1-alpha antibodies in human serum or plasma. (REF: 25001)

Ribosomal P ELISA

  • ELISA for the semi-quantitative determination of anti-Ribosomal P antibodies in human serum or plasma. (REF: 25002)

Scl-70 ELISA

  • ELISA for the semi-quantitative determination of anti-Scl-70 antibodies in human serum or plasma. (REF: 25003)

CENP ELISA

  • ELISA for the semi-quantitative determination of anti-CENP antibodies in human serum or plasma. (REF: 25004)

dsDNA ELISA

  • ELISA for the semi-quantitative determination of anti-dsDNA antibodies in human serum or plasma. (REF: 25005)

Ro52 ELISA

  • ELISA for the semi-quantitative determination of anti-Ro52 antibodies in human serum or plasma. (REF: 25006)

Ro60 ELISA

  • ELISA for the semi-quantitative determination of anti-Ro60 antibodies in human serum or plasma. (REF: 25007)

La ELISA

  • ELISA for the semi-quantitative determination of anti-La antibodies in human serum or plasma. (REF: 25008)

Jo-1 ELISA

  • ELISA for the semi-quantitative determination of anti-Jo-1 antibodies in human serum or plasma. (REF: 25009)

Sm ELISA

  • ELISA for the semi-quantitative determination of anti-Sm antibodies in human serum or plasma. (REF: 25010)

RNP / Sm ELISA

  • ELISA for the semi-quantitative determination of anti-RNP / Sm antibodies in human serum or plasma. (REF: 25011)

ANA Screen ELISA

  • ELISA for the semi-quantitative determination of anti-nuclear antibodies in human serum or plasma. (REF: 25012)

SLE Profile 4 ELISA

  • ELISA for the semi-quantitative determination of 4 SLE-associated antibodies in human serum or plasma. (REF: 25019)

SLE Profile 6 ELISA

  • ELISA for the semi-quantitative determination of 6 SLE-associated antibodies in human serum or plasma. (REF: 25021)

ENA Profile 8 ELISA

  • ELISA for the semi-quantitative determination of autoantibodies against extractable nuclear antigens (ENA) in human serum or plasma. (REF: 25023)

CENP-A ELISA

  • ELISA for the semi-quantitative determination of anti-CENP-A antibodies in human serum or plasma. (REF: 25024)

Systemic autoimmune diseases:

  • Rheumatoid arthritis 

  • Lupus erythematosus 

  • Polymyositis 

  • Sjogren's Syndrome 

  • Scleroderma 

  • Systemic vasculitis 

AUTOIMMUNE LATERAL FLOW ASSAY

AI-LFA Pr3

AI-LFA Pr3 (Autoimmune Lateral Flow Assay) is a rapid test for the qualitative determination of proteinase 3 (Pr3) specific IgG autoantibodies in human serum or plasma. The AI-LFA enables the user to carry out a specific autoimmune test very quickly and reliably. (REF: 186025)

AI-LFA MPO

AI-LFA MPO (Autoimmune Lateral Flow Assay) is a rapid test for the qualitative determination of myeloperoxidase (MPO) specific IgG autoantibodies in human serum or plasma. The AI-LFA enables the user to carry out a specific autoimmune test very quickly and reliably. (REF: 186026)

AI-LFA GBM

AI-LFA GBM (Autoimmune Lateral Flow Assay) is a rapid test for the qualitative determination of anti-glomerular basement membrane (GBM) specific IgG autoantibodies in human serum or plasma. The AI-LFA enables the user to carry out a specific autoimmune test very quickly and reliably. (REF: 186027)

AI-LFA dsDNA

AI-LFA dsDNA (Autoimmune Lateral Flow Assay) is a rapid test for the qualitative determination of anti-dsDNA-specific IgG autoantibodies in human serum or plasma. The AI-LFA enables the user to carry out a specific autoimmune test very quickly and reliably. (REF: 186028)